My laboratory investigates the behavioral significance of amines in complex behavioral phenomena such aggression and drug addiction. Using simpler systems approaches we mostly study these behaviors in invertebrates with a combination of neuroethological, pharmacological, and molecular approaches. Towards this goal I am interested in the neurochemical mechanisms underlying motivational states in behavior. Questions such as "why does an animal perform behavior A as opposed to behavior B at a specific point in time?" motivate my research program. The highly structured behavior of crayfish, which have relatively 'simple' nervous systems, allows us to explore the neural basis of motivational mechanisms at levels which are difficult to achieve in most other species, including mammals. We offer expertise in quantitative, behavioral analysis, automated behavioral screening, dynamic and self-structuring properties, neural designs and neurochemical measures.
Huber R, Bannasch D & P Brennan. 2011. Aggression. Advances in Genetics Vol. 75. Hardbound, 216 Pages, ISBN 13: 978-0-12-380858-5, Elsevier Academic Press.
Donelson N, Kim EZ, Slawson JB, Vecsey CG, Huber R & LC Griffith. 2012. High-resolution long-term tracking for analysis of Drosophila sleep and locomotion. PLoS ONE 7(5): e37250
Nathaniel T, Panksepp J & R Huber. 2012. A New Path in Drug Addiction Research: The Crayfish Model and Morphine-Sensitive Reward. Adv. Med. Biol. 45: 207-214
Nathaniel T, Panksepp J & R Huber. 2012. Alteration of c-Fos mRNA in the accessory lobe of crayfish is associated with a conditioned-cocaine induced reward. Neurosci Res. 72: 243-256
Nathaniel T, Huber R & J Panksepp. 2012. Repeated cocaine treatments induce distinct locomotor effects in Crayfish. Brain Research Bull. 87:328-333
Alcaro, A, Panksepp J & R Huber. 2011. D-amphetamine stimulates unconditioned exploration/approach behaviors in crayfish: towards a conserved evolutionary explanation of ancestral drug reward. Psychopharm. 99(1): 75-80
Daws AG, Hock K & R Huber. 2011. Spatial structure of hierarchical groups: testing for processes of aggregation, clustering, and spatial centrality in crayfish (Orconectes rusticus). Mar. Freshwater Behav. Physiol. 44(4): 209-222
Huber R, Panksepp JB, Nathaniel T, Alcaro A & J Panksepp. 2011. Drug-sensitive reward in crayfish: An invertebrate model system for the study of SEEKING, reward, addiction, and withdrawal. Neurosci. & Biobehav. Rev. 35(9): 1847-1853
Nathaniel TI, Panksepp J & R Huber. 2010. Effects of a single and repeated morphine treatment on conditioned and unconditioned behavioral sensitization in crayfish. Behavioural Brain Research 207(2): 310-320