My laboratory investigates the behavioral significance of amines in complex behavioral phenomena such aggression and drug addiction. Using simpler systems approaches we mostly study these behaviors in invertebrates with a combination of neuroethological, pharmacological, and molecular approaches. Towards this goal I am interested in the neurochemical mechanisms underlying motivational states in behavior. Questions such as "why does an animal perform behavior A as opposed to behavior B at a specific point in time?" motivate my research program. The highly structured behavior of crayfish, which have relatively 'simple' nervous systems, allows us to explore the neural basis of motivational mechanisms at levels which are difficult to achieve in most other species, including mammals. We offer expertise in quantitative, behavioral analysis, automated behavioral screening, dynamic and self-structuring properties, neural designs and neurochemical measures.
Huber R, Bannasch D & P Brennan. 2011. Aggression. Advances in Genetics Vol. 75. Hardbound, 216 Pages, ISBN 13: 978-0-12-380858-5, Elsevier Academic Press.
Hughson BN, Anreiter I, Jackson Chornenki NL, Murphy KR, Ja WW, Huber R & MB Sokolowski. 2017. The adult foraging assay (AFA) detects strain and food-deprivation effects in feeding-related traits of Drosophila melanogaster. J Insect Physiol. S0022-1910(17)30108-7. PMID: 28860037; PubMed Central PMCID: PMC5832525
Murphy KR, Park JH, Huber R, & WW Ja. 2017. Simultaneous measurement of sleep and feeding in individual Drosophila, Nature Protocols 12, 2355–2366. doi:10.1038/nprot.2017.096
Murphy KR, Deshpande SA, Yurgel ME, Quinn JP, Weissbach JL, Keene AC, Dawson-Scully K, Huber R, Tomchik SM & WW Ja. 2016. Postprandial sleep mechanics in Drosophila. eLife 2016;5:e19334. doi:10.7554/eLife.19334
Donelson N, Kim EZ, Slawson JB, Vecsey CG, Huber R & LC Griffith. 2012. High-resolution long-term tracking for analysis of Drosophila sleep and locomotion. PLoS ONE 7(5): e37250
Alcaro A, Huber R & J Panksepp. 2007. Behavioral functions of the mesolimbic dopaminergic system: an affective neuroethological perspective. Brain Research Rev. 56(2): 283-321
Nilsen SP, Chan Y-B, Huber R & EA Kravitz. 2004. Gender-selective patterns of aggressive behavior in Drosophila melanogaster. Proc. Nat. Acad. Sci. 101 (33): 12342-12347
Chen S, Lee AY, Bowens NM, Huber R & EA Kravitz. 2002. Fighting fruit flies: a model system for the study of aggression. Proc. Nat. Acad. Sci. 99(8): 5664-5668
van Staaden M & R Huber. 2001. Multidisciplinary dissection of behavioral arousal: The role of muscarinic acetylcholine stimulation in grasshopper stridulatory behavior. Proc. Nat. Acad. Sci. 98(17): 9468–9470