Xiaohong Tan, Ph.D.
211 Physical Sciences Laboratory Building
Joined the faculty in 2019
Ph.D, Nanyang Technological University 
M.S., Sichuan University 
B.A., Sichuan University 
Our research activities are mainly in the areas of protein biochemistry, peptide/protein chemistry, bioanalytical chemistry, chemical biology, and bioengineering. Our research aim is to develop next-generation platform for disease diagnostics and therapy. To realize this aim, we are interested in playing with Nature's building blocks, peptide, protein, DNA and RNA.
Topics of interest:
Fluorescent hairpins, peptide/protein chemistry, aptamer, antibody delivery, antibody mimics
Tan, X.; Bruchez, M.P.; Armitage, B.A. "Efficient Cytoplasmic Delivery of Antisense Probes Assisted by Cyclized‐Peptide‐Mediated Photoinduced Endosomal Escape," ChemBioChem, 2019, 20 (5), 727-733.
Tan, X.; Yang, R.; Liu, C. "Facilitating Subtiligase-Catalyzed Peptide Ligation Reactions by Using Peptide Thioester Substrates," Org. Lett., 2018, 20 (21), 6691-6694.
Tan, X.; Bruchez, M.P.; Armitage, B.A. "Closing the Loop: Constraining TAT Peptide by γPNA Hairpin for Enhanced Cellular Delivery of Biomolecules," Bioconjug., Chem., 2018, 29 (9), 2892-2898.
Tan, X.; Constantin, T.P.; Sloane, K.L.; Waggoner, A.S.; Bruchez, M.P.; Armitage, B.A. "Fluoromodules Consisting of a Promiscuous RNA Aptamer and Red or Blue Fluorogenic Cyanine Dyes: Selection, Characterization, and Bioimaging," J. Am. Chem. Soc., 2018, 139 (26), 9001-9009.
Tan, X.; Armitage, B.A.; Bruchez, M.P. "Label-free Molecular Beacons for Biomolecular Detection," Anal. Chem., 2014, 86 (21), 10864–10869.
Tan, X.; Chen, T.; Xiong, X.; Mao, Y.; Zhu, G.; Yasun, E.; Li, C.; Zhu, Z.; Tan, W. " Semi-quantification of ATP in Live Cells using Nonspecific Desorption of DNA from Graphene Oxide as the Internal Reference," Anal. Chem., 2012, 84 (20), 8622-8627.
Updated: 01/25/2023 02:27PM