Agilent 1260 Infinity II LC

chemistryagilent1260
The Agilent 1260 Infinity II LC
is a cornerstone of the Center’s analytical capabilities. As a versatile and robust High-Performance Liquid Chromatography (HPLC) system, it provides the essential separation and quantification power needed to analyze the complex reaction mixtures typical of photochemical research.

In an environment where light-driven reactions often yield multiple products, isomers, or intermediates, the Infinity II ensures that CPS researchers can monitor reaction progress with high precision and reproducible results.

## Critical Research Benefits

  • Reaction Monitoring and Kinetics: The Infinity II allows CPS scientists to track the disappearance of starting materials and the emergence of photoproducts over time. This is fundamental for calculating quantum yields and understanding the efficiency of new photochemical pathways.

  • Purity Verification: Before performing high-end spectroscopic measurements (like femtosecond laser studies), it is vital to ensure that synthetic dyes or catalysts are ultra-pure. This HPLC system provides the "gold standard" for purity analysis, preventing impurities from skewing delicate photophysical data.

  • Separation of Photostationary States: For researchers working on molecular switches and photochromic materials, the system is used to separate and quantify different isomers (such as cis-trans mixtures) generated under specific light conditions.

  • Complex Mixture Analysis: In environmental photochemistry, where light is used to degrade pollutants, the Infinity II is used to identify the various breakdown products, helping our researchers assess the safety and efficacy of new water treatment technologies.

## Key Technical Advantages

Feature

Advantage for CPS Research

Modular Stack Design

Can be easily configured with different detectors (UV-Vis, Fluorescence, or MS) to suit specific project needs.

High Pressure Range

Supports the use of modern, small-particle columns for faster separations and higher resolution.

Advanced Autosampler

Enables unattended overnight analysis of up to 132 samples, maximizing lab productivity.

Low Carryover

Specialized needle-wash technology ensures that trace amounts of one sample do not contaminate the next.

## Strategic Impact at the Center

As the CPS celebrates 40 years of excellence, the Agilent Infinity II represents the practical side of our scientific innovation:

  • Interdisciplinary Utility: It is a shared resource used equally by synthetic chemists, biological researchers studying protein-dye conjugates, and materials scientists.

  • Industry-Ready Training: Because Agilent is a global leader in chromatography, CPS graduate students gain hands-on experience with the same software (OpenLab) and hardware used in top pharmaceutical and industrial R&D labs.

  • Reliability and Uptime: Its robust design and self-diagnostic features ensure that the system remains operational for the heavy daily workloads of our diverse research groups, keeping our projects on schedule.

Operator Note: The system is currently configured with a Quaternary Pump, allowing for complex four-solvent gradients. Please ensure that all mobile phases are HPLC-grade and have been filtered and degassed prior to use to protect the pump seals and column.

Updated: 04/24/2026 04:38PM