Ostrowski

Joined the faculty in 2012
Ph.D, University of California, Santa Barbara (2010)
B.A., Occidental College (2004)

Alexis D. Ostrowski, Ph.D.

Professor, Associate Dean
511 Physical Sciences Laboratory Building
419-372-2809
alexiso@bgsu.edu

Research Group Website

Research Interests:

Our research is inspired by the interactions of metal ions in natural systems. We focus on the fundamental photochemistry of metal-coordination interactions in polymers and are also interested in understanding how the photochemical reactions of contribute to metal ion cycling in the watershed. In addition, we use this photochemistry as inspiration, creating new photo-responsive materials. We use coordination complexes, biopolymers, and nanoparticles to design the photo-responsive materials. We have designed photoresponsive materials for wastewater treatment and sustainable bioplastics, and are investigating how the metal ion coordination affects degradation and mechanical properties of the materials. We are also interested in how these biodegradable materials can influence nutrient cycling, plant growth, and microbial communities at the agricultural/watershed interface, particularly in coastal systems like the Great Lakes.

Topics of interest:

photochemistry, materials science, coordination chemistry, polymer synthesis, metals in biology, nanoparticle assembly, biomaterials  

Graduate students:

Fatima Naser Aldine (she/her): 2023-present

Shaya Khosravibavandpoori (she/her): 2023-present

Sayani Nimanka (she/her): 2026-present

Undergraduate students:

Lucy Busselle (she/her): 2024-present

Maile Prater (she/her): 2025-present

Graduate:

Ebenezer Adom Mensah (he/him): MS awarded, 2025

Rahimon Naher (she/her): MS student, 2025

Dr. Irene Baraza (she/her), PhD Awarded 2025

Cori Byrge (she/her), MS Biology student 2020-2023

Shabna Nazim, MS awarded 2023

Dr. Ankit DaraPhD awarded 2023

Dr. Carina Haddad, PhD awarded 2022

Dr. Kalani Edirisinghe, PhD awarded 2022

Dr. Jayan Karunarathna, PhD awarded 2020

Dr. Travis Green, PhD awarded 2020

Dr. Anton RazgoniaevPhD awarded 2017

Dr. Giuseppe Giammanco, PhD awarded 2016

Dayana Muizzi, MS awarded 2015

Undergraduate:

Khang Van (he/him): 2025

Ellis Harlan Puthoff: BS Forensic Sciences awarded 2023; 2022-2023

Hope Brown: BS Chemistry awarded 2021; 2020-2021

Derek Mast: BS Chemistry awarded 2019; Summer-Fall 2019

Kerri Bailey: BS Biochemistry awarded 2019, 2018- 2019

Rachel BianculliBS Chemistry awarded 2018, 2017-2018

Zachery Hatten, BGSU, BS Chemistry awarded 2018, 2017-2018

Jacob Medina, Summer intern from St. Marys, Summer 2017

Jackson Chory: BGSU undergrad, 2015-2017

Bethany Abbott: BGSU undergrad, Summer 2016

Kirill Mikhalov, summer intern from St. Petersburg, Russia; Summer 2015, 2016

Ivan Mosiagin, summer intern from St. Petersburg, Russia; Summer 2016

Erin Kielmeyer, Chemistry major, BGSU; 2015-2016

Joshua Chaffins, Chemistry major, BGSU; Summer 2015

Jon Mase, BS Biochemistry awarded 2015;  2013-2015

Chris Sosnofsky, BS Biochemistry awarded 2015;  2013-2015

CJ Reed, BS Chemistry awarded 2015; Fall 2014

Filipp Obrezkov, summer intern from St. Petersburg, Russian Federation; Summer 2014

OstrowskiGroup - 1

Polymers + Photochemistry

Photoresponsive materials for nitric oxide release

In collaboration with the Furgal Materials Workshop, our group is designing new photoresponsive silsesquioxane materials that release NO after light irradiation. We are particularly focused on creating materials with controlled release after NIR light irradiation. This project is funded by the NIH.

A Bioinorganic approach to photoresponsive bioplastics

We are currently working to use plant-derived polymers-specifically those typically thought of as waste products- and metal coordination bonding, to create new materials with advanced mechanical properties (stiffness, elasticity) that mimic the hierarchical structure found in nature. We are designing these materials to be robust enough for packaging, but biodegradable enough to decompose completely in a landfill or compost conditions.

Dynamics and photochemistry in metallopolymer materials

We are creating supramolecular materials that rely on metal-coordination bonding interactions to give them unique photochemistry and mechanical properties.  This project is currently focused on understanding how changes in metal coordination bonding dynamics can be used to sense mechanical property changes in the materials.

Biogeochemistry of Fe(III)-polysaccharide hydrogels

In collaboration with BGSU’s Center for Great Lakes Center and Watershed Studies, we are investigating the biogeochemistry of Fe(III)-polysaccharide hydrogels in both soil and water, including how they can be used for recycling of nutrients like phosphate to prevent nutrient run-off.

Publications

From 2025:

E.A.K.D. Edirisinghe; M.J. Ayodele; S. Saeedi; A.M. Brugh; M.D.E. Forbes; T.A. White; A.D. Ostrowsk; “Reversible photochemistry in vanadium (V) tartrate clusters containing a mixed-valent intermediate”

Naser Aldine F, Muizzi DA, Baraza IF, Furgal JC, Ostrowski AD. Tuning Quantum Yield to Maximize Nitric Oxide Release Under Red and NIR Light in Photoresponsive Ruthenium Salen Materials . ChemRxiv2025; doi:10.26434/chemrxiv-2025-hgplj

Older:

Edirisinghe, E.A.K.D.; Haddad, C.; Ostrowski, A.D; “Controlled and Photopatterning of Mechanical properties in polysaccharide hydrogels using vanadium coordination and photochemistry” ACS Applied Bio Materials, 2022, 5, 10, 4827 DOI: 10.1021/acsabm.2c00529

Dara, A.; Mast, D. M.; Razgoniaev, A.O.; Hauke, C.; Castellano, F. N.; Ostrowski, A.D; “Real-time and in situ viscosity monitoring in industrial adhesives using luminescent Cu(I) phenanthroline molecular sensors” ACS Applied Materials and Interfaces, 2022, 14, 2933976–33983 DOI: 10.1021/acsami.2c06554

Haddad, C.; Edirisinghe, E.A.K.D.; Brown, H. M; Ostrowski, A.D; “Photoreactivity and enhanced mechanical properties and water stability in polysaccharide based films using vanadium ion coordination” ACS Applied Polymer Materials, 2022, 4, 2, 859–867 DOI: 10.1021/acsapm.1c01371

Karunarathna, M. H. J. S; Linhart, A.; Giammanco, G.E.; Norton, A.; Chory, J.; Keleher, J. ; Ostrowski, A.D.; “Harnessing Fe(III)-carboxylate photochemistry for radical initiated polymerization in hydrogels” ACS Applied Bio Materials20214, 7, 5765–5775 DOI: 10.1021/acsabm.1c00525

A. Butler; T. Harder; A.D. Ostrowski; C.J Carrano. “Photoactive Siderophores; Structure Function and Biology” J Inorg Biochem2021DOI: 10.1016/j.jinorgbio.2021.111457

M.J. Ayodele;  T.C. Green; W.A.C.V. Warsapperuma; M.D.E. Forbes; A. D. Ostrowski; “Synthesis and crystal structure of catena-poly[[tetra-μ-acetato-copper(II)]-μ-6-eth­­oxy-N2,N4-bis­­[2-(pyridin-2-yl)eth­yl]-1,3,5-triazine-2,4-di­amine]” Acta Crystallographica E2021, 77, 319-323 DOI

Karunarathna, M. H. J. S.; Ayodele, M. J.; Giammanco, G. E.; Brugh, A. M.; Muizzi, D. A.; Bauman, M. A.; Torelli, A. T.; Alabanza, A. M.; Forbes, M. D. E.; Ostrowski, A. D. “Fe(III)-Polyuronic Acid Photochemistry: Radical Chemistry in Natural Polysaccharides.” Photochemical and Photobiological Sciences, 2021, 20, 255–263  DOI: 10.1007/s43630-021-00014-0

Karunarathna, M. H. J.; Bailey, K. M.; Ash, B.; Matson, P.G.; Wildschutte, H.; Davis, T.; Midden, W. R.; Ostrowski, A.D.; “Nutrient capture from aqueous waste and photo-controlled fertilizer delivery to tomato plants using Fe(III)–polysaccharide hydrogels”, ACS Omega 20205, 36, 23009–23020 DOI:/10.1021/acsomega.0c02694

Green, T.C.; Gresh, R.; Cochran, D.; Crobar, K.; Blass, P.; Ostrowski, A.D.; Campbell, D.; Xie, C.; Torelli, A.; “Invisibility Cloaks and Hot Reactions: Applying Infrared Thermography in the Chemistry Education Laboratory” J. Chem. Ed. 2020, 97, 710-718 DOI: 10.1021/acs.jchemed.9b00789

Karunarathna, M. H. J.; Hatten, Z.; Bailey, K.; Lewis, E.; Morris, A.; Kolk, A.; Laib, J.; Tembo, N.; Williams, R.; Phillips, B.; Ash, B.; Midden, W. R.; Ostrowski, A.D.; “Reclaiming phosphate from waste solutions with Fe(III) –polysaccharide hydrogel beads for photo-controlled-release fertilizer” Journal of Agricultural and Food Chemistry, 201967, 12155-12163 DOI: 10.1021/acs.jafc.9b02860* front cover article

M.Y. Livshits, A.O. Razgoniaev, R.C. Arbulu, J. Shin, B.J. McCullough , Y.Qin, A. D. Ostrowski, J.J. Rack; “Generating Photonastic Work from Irradiated Dyes in Electrospun Nanofibrous Polymer Mats” ACS Appl. Mater. Interfaces2018, 10, 37470–37477, DOI: 10.1021/acsami.8b11294

A.O Razgoniaev; K.I. Mikhailov; F.A. Obrezkov; E.V. Butaeva; A. D. Ostrowski; “Supramolecular Elastomers: Switchable Mechanical Properties and Tuning Photohealing with Changes in Supramolecular Interactions” Journal of Polymer Science: Polymer Chemistry201856, 1003-1011 DOI: 10.1002/pola.28972

25.) H. Auerbach; G.E. Giammanco; V. Schünemann; A. D. Ostrowski; C.J. Carrano “Mössbauer Spectroscopic Characterization of Iron (III)-Polysaccharide Coordination Complexes: Photochemistry, Biological and Photoresponsive Materials Implications” Inorganic Chemistry, 2017, 56, 11524, DOI: 10.1021/acs.inorgchem.7b00686

24.) A. O. Razgoniaev; C. E. McCusker; F. N. Castellano; A. D. Ostrowski “Restricted Photoinduced Conformational Change in Cu(I) Complex for Sensing Mechanical Properties” ACS Macro Letters, 20176, 920-244 DOI: 10.1021/acsmacrolett.7b00465

23.) Moroz, P.; Razgoniaeva, N.; Vore, A.; Eckard, H.; Kholmicheva, N.; McDarby, A.; Razgoniaev, A.; Ostrowski, A.D.; Khon, D.; Zamkov, M. “Plasmon Induced Energy Transfer: When the Game is worth the Candle” ACS Photonics, 2017, 4, 2290 DOI: 10.1021/acsphotonics.7b00527

22.)J. Storer; J. Chao; A.T. Torelli; A.D. Ostrowski “KnoWare: A System for Citizen-based Environmental Monitoring” Informing Science: the International Journal of an Emerging Transdiscipline201619,125-139 full text

21.) G.E. Giammanco; B.Carrion; R.M. Coleman; A.D. Ostrowski “Photoresponsive Polysaccharide-based Hydrogels with Tunable Mechanical Properties for Cartilage Tissue Engineering”, ACS Appl. Mater. Interfaces20168, 14423-14429 DOI: 10.1021/acsami.6b03834

20.) A.O.Razgoniaev; E.V.Butaeva; A.V. Iretskii; A.D. Ostrowski “Changing mechanical strength in Cr(III)-metallosupramolecular polymers with ligands and light”, Inorganic Chemistry201655, 5430-5437 DOI: 10.1021/acs.inorgchem.6b00422

19.) G.E. Giammanco; A.D. Ostrowski “Photo-Patterning the mechanical properties of Polysaccharide-containing gels using Fe3+ coordination”, Chemistry of Materials201527, 4922-4925, DOI: 10.1021/acs.chemmater.5b01727

18.) G.E. Giammanco; C.T. Sosnofsky; A.D. Ostrowski “Light-responsive Iron(III)-Polysaccharide Coordination hydrogels for controlled delivery” ACS Applied Materials and Interfaces20157, 3068-3076 DOI: 10.1021/am506772x

17.) N. Razgoniaeva; S. Lambright; N. Sharma; A. Acharya; E. Khon; P. Moroz; A.O. Razgoniaev; A.D. Ostrowski; M. Zamkov; “Exciton Generation in Semiconductor Nanocrystals via the Near-Field Plasmon Energy Transfer” J. Phys. Chem. C 2015DOI: 10.1021/acs.jpcc.5b04608

16.) J.D. Mase; A.O. Razgoniaev; M.K. Tschirhart; A.D. Ostrowski “Light- controlled release of nitric oxide from solid polymer composite materials using visible and near infra-red light,” Photochemical and Photobiological Sciences 201514, 775-785 DOI: 10.1039/C4PP00441H

15.) N.N. Kholmicheva; P. Moroz; U. Rijal; E. Bastola; P. Uprety; G. Liyanage; A.O. Razgoniaev; A.D. Ostrowski; M. Zamkov; “Plasmonic nanocrystal solar cells utilizing strongly confined radiation” ACS Nano 20148, 12549-12559, DOI: 10.1021/nn505375n

14.) A. Pierri; D. A. Muizzi; A.D. Ostrowski; P.C. Ford “Photo-controlled release of NO and CO with metal complexes,” Structure and Bonding2014, DOI: 10.1007/430_2014_164

13.) D. J. Gargas; E. M. Chan; A. D. Ostrowski; B. A. Sanii; E. S. Barnard; A. Nievergelt; S.A. Aloni; D.A. Milliron; B.E. Cohen; P.J. Schuck “Engineering Bright Sub-10-nm Upconverting Nanocrystals for Single-Molecule Imaging,” Nature Nanotechnology 2014, 9, 300-305. DOI:10.1038/nnano.2014.29

12.) E. M. Chan; G. Han; J. D. Goldberg; D. J. Gargas; A. D. Ostrowski; P. J. Schuck; B. E. Cohen; D. J. Milliron; ” Combinatorial discovery of lanthanide-­doped nanocrystals with spectrally pure upconverted emission,” Nano Lett 201212, 3839–3845. DOI: 10.1021/nl3017994

11.) A. D. Ostrowski; E. M. Chan; D. J. Gargas; E. M. Katz; G. Han; P.J. Schuck; D.J. Milliron; B.E.Cohen. “Controlled synthesis and single particle imaging of bright, sub-10 nm lanthanide-doped upconverting nanocrystals,” ACS Nano 2012, 6, 2686–2692. DOI: 10.1021/nn300073

10.) A. D. Ostrowski; B.F.Lin; M.V.Tirrell; P.C.Ford. “Liposome encapsulation of a photochemical NO precursor for controlled nitric oxide release and simultaneous fluorescence imaging,” Molecular Pharmaceutics, 2012, 9, 2950-2955. DOI: 10.1021/mp300139y

9.) P.T. Burks; A.D. Ostrowski; A.A. Mikhailovsky; E.M. Chan; P.S. Wagenknecht; P. C. Ford. “Quantum Dot Photoluminescence Quenching by Cr(III) Complexes. Photosensitized Reactions and Evidence for a FRET Mechanism,” JACS 2012, 134, 13266–13275. DOI: 10.1021/ja300771w

8.) A. D. Ostrowski; R.O. Absalonson; M. A. De Leo; G. Wu; J. G. Pavlovich; J. Adamson; A. V. Iretskii; I. L. Megson; P. C. Ford. “The Photochemistry of trans-Cr(cyclam)(ONO)2+, a Nitric Oxide Precursor,” Inorg. Chem. 201150, 4453–4462. DOI: 10.1021/ic200094x

7.) A. D. Ostrowski; S. J. Deakin; B. Azhar; T. W. Miller; N. Franco; M. M. Cherney; A. J. Lee; J. N. Burstyn; J. M. Fukuto; I. L. Megson; P. C. Ford. “Nitric Oxide Photogeneration from trans-Cr(cyclam)(ONO)2+ in a Reducing Environment. Activation of Soluble Guanylyl Cyclase and Arterial Vasorelaxation,” J. Med. Chem. 2010, 53, 715–727. DOI: 10.1021/jm9013357

6.) A. D. Ostrowski and P. C. Ford. “Metal complexes as photochemical nitric oxide precursors: Potential applications in the treatment of tumors.” Dalton Trans.2009, 10660 – 10669. DOI: 10.1039/B912898K

5.) A. D. Ostrowski; T. Martin, J. Conti; I. Hurt; B. H. Harthorn. “Nanotoxicology: characterizing the scientific literature, 2000–2007,” J. Nano. Res.2009, 11, 251-257. DOI: 10.1007/s11051-008-9579-5

4.) D. Neuman; A. D. Ostrowski; A. A. Mikhailovsky; R. O. Absalonson; G. F. Strouse; P. C. Ford.  “Quantum Dot Fluorescence Quenching Pathways with Cr(III) Complexes. Photosensitized NO Production from trans-Cr(cyclam)(ONO)2+,” JACS2008, 130, 168. DOI: 10.1021/ja074164s

3.) D. Neuman; A. D. Ostrowski; R. O. Absalonson; G. F. Strouse; P. C. Ford. “Photosensitized NO Release from Water Soluble Nanoparticle Assemblies,” JACS2007, 129, 4146-4147. DOI: 10.1021/ja070490w

2.) R. E. Anderson; A. D. Ostrowski; D. E. Gran; J. D. Fowler; A. R. Hopkins; R. M. Villahermosa. “Diameter-Controlled Synthesis of Polyaniline Nanofibers,” Polymer Bulletin2008, 61, 563-568. DOI: 10.1007/s00289-008-0983-x

1.) R. M. Villahermosa and A. D. Ostrowski. “Chemical analysis of silicone outgassing,”. Proc. SPIE 2008, 7069, 706906. DOI: 10.1117/12.802311

Updated: 04/14/2026 04:35PM