Dr. Roudabeh J. Jamasbi
Ph. D., University of Arkansas
Research: Cancer immunology, microbiology
Cancer immunology, microbiology: The research interest of this investigator has been focused on the biological and immunological characterization of cancer cells. In the course of these studies both in vivo and in vitro tumor lines have been established and studied in detail. Currently, however, emphasis has been placed on the role of tumor heterogeneity on the process of tumor progression, metastasis and radiation sensitivity. Cytogenetic abnormalities of these lines are also being investigated.
Monoclonal antibodies (MAbs) directed against tumor associated antigens in experimental animal models have been produced and characterized. More recently, MAbs to human tumor systems have also been produced and characterized. Development of monoclonal antibodies to clinically significant microorganisms is another branch of the research interest in our program.
AlManaa, T.N, M.E. Geusz and R.J. Jamasbi. 2012. Effect of curcumin on stem-like sub population in human esophageal squamous cell carcinoma cell lines. (submitted)
Yan, D., M.E. Geusz and R.J. Jamasbi. 2012. Properties of Lewis lung carcinoma cells surviving curcumin toxicity. Journal of Cancer 3:32-41.
Geusz, M.E., K.T. Blakely, D.J. Hiler and R.J. Jamasbi. 2010. Elevated mPer1 gene expression in tumor stroma imaged through bioluminescence. International Journal of Cancer 126:620-30.
Jamasbi, R.J., and N.M. Taylor. 2010. Correlation between the lipopolysaccharide expression and adhesiveness of clinical isolates of Pseudomonas aeruginosa. Lab Medicine 41:24-30.
Jamasbi, R.J. and E.M. Proudfoot. 2008. Phenotypic and genotypic characteristics of P. aeruginosa clinical isolates: rate of occurrences of different serotypes antimicrobial susceptibility profiles and molecular typing. Lab Medicine 39:155-161.
Jamasbi, R.J. and E.M. Proudfoot. 2007. Determination of genotypic profiles of clinical isolates of P. aeruginosa. ASM 107.
Jamasbi, R.J., A.R. Chakraborty, S.J. Kennel. 2006. Differential expression of α3β1 and α6β4 integrin molecules on different rat and human esophageal cell lines. AARC 47:526.
Jamasbi, R.J., S. J. Kennel, L.C. Waters, L.J. Foote and J.M. Ramsey. 2004. Genetic Analysis of Pseudomonas aeruginosa by enterobacterial repetitive intergenic consensus polymerase chain reaction (PCR) and arbitrarily primed PCR: gel analysis compared with microchip gel electrophoresis. Infection Control and Hospital Epidemiology Vol. 25 65-71.