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Research Professor
Office: 310 Physical Sciences Laboratory Building
Phone: (419) 372-2035
Email: rmw@bgsu.edu
Biographical Facts
Joined the faculty in 2005
Ph.D., Massachusetts Institute of Technology (1965)
B.S., The Pennsylvania State University (1961)
Research Interests
Our
research interests are directed towards photochemical application of lasers,
primarily argon ion lasers, and fall into two broad categories: the laser
synthesis of new materials and the development of reagents for the photochemical
manipulation of biological systems. These include:
- The
use of CW laser plasmas to prepare carbon bowls, Bucky Bowls and the study
of the properties of these bowl-shaped “aromatic” hydrocarbons.
- The development of new reagents for the photochemical cross-linking of nucleic acids, primarily RNA, with proteins.
- The development of new reagents for the photochemical cleavage of nucleic acids, primarily RNA.
- The
development of the aforementioned two techniques to study the interactions
between nucleic acids and proteins using mass spectrometry to obtain detailed
structural information about the nature of these interactions
Selected Publications
“The
Vocabulary of Organic Chemistry”, 2nd Edition, Wiley-Interscience, 2005,
with Milton Orchin, Allan Pinhas, and Roger Macomber.
“Photoaffinity
Labeling with 8-Azidoadenosine and Its Derivatives: The Chemistry of Closed
and Open Adenosine Diazaquinodimethanes”, Biochemistry, 2005, 44,
11241-11253, with Dmitrii Polshakov, Saroj Rai, Eric T. Mack, Martin Vogel,
Jeanette Krause, Gotard Burdzinski, and Matthew S. Platz.
“DNA Photocleavage and Biological Activity of a Pyrene Dihydrodioxin”, Bioorganic and Medicinal Chemistry Letters, 2005, 15, 2173-2176, with Eric T. Mack, Dagne Birzniece, Darren Veach, and William Coyle.
“Thermal and Photochemistry of a Pyrene Dihydrodioxin (PDHD) and Its Radical Cation: A Photoactivated Masking Group for ortho-Quinones”, Journal of the American Chemical Society, 2004, 126, 15324, with Eric T. Mack, A. Björn Carle, and J. T.-M. Liang, W. Coyle.
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