| |

Professor and Chair
Office: 138C Overman Hall
Phone: (419) 372-9231/2809
Email: mogawa@bgsu.edu
Personal site: Visit
Biographical Facts
Joined the faculty in 1991
Ph.D., Northwestern University (1988)
M.S., Northwestern University (1983)
B.A., Oberlin College, Ohio (1980)
Research Interests:
Our group is developing a new class of
hybrid inorganic/biological materials possessing novel photochemical
properties.
In one project we are using the principles of “metalloprotein design”
to
prepare a new class of miniature metalloproteins containing luminescent
Cu(I)
centers. The photophysical properties of these systems have been
found
to mimic many features found in natural photosynthetic reaction centers
and
can be used to develop new routes towards solar energy
conversion.
A related project uses supramolecular coordination chemistry to direct
the
assembly of novel peptide structures. We have found that such
metal-mediated
peptide assemblies possess a diverse range of morphologies ranging from
nanometer-scale
hollow spheres to nano-cylinders, making them possible candidates for
drug
delivery vehicles. Thus, a central theme of our laboratory is to
combine
inorganic coordination chemistry/photochemistry with protein design in
order
to prepare new types of hybrid materials which possess potentially
useful
chemical properties.
Selected Publications:
Metal-mediated Peptide Assembly:
Use of Metal Coordination to Change the Oligomerization State of an
α-helical Coiled-coil, Tsurkan, M. V. and Ogawa, M Y., Inorg. Chem. 2007, 46, 6849-6851.
Electron-Transfer Functionality into Synthetic Metalloproteins from the
Bottom-up, (Inorganic Forum Article), Hong, J, Kharenko, O. A. and
Ogawa, M. Y., Inorg. Chem. 2006, 45, 9974-9984.
Electron-Transfer Functionality of Synthetic Coiled-coil
Metalloproteins, Ogawa, M. Y., Fan, J., Fedorova, A., Hong, J.
Kharenko, O. A., Kornilova, A. Y., Lasey, R. C., Xie, F. J. Braz. Chem. Soc. 2006, 17, 1516-1521.
A Miniature Cu(I) Metalloprotein Undergoes Collisional
Electron-transfer in the Inverted Marcus Region, J. Hong, O. A.
Kharenko, A. K. Petros, B. R. Gibney, and M. Y. Ogawa, Angew. Chem. Int. Ed. 2006, 37, 6137-6140.
Cu(I) Luminescence from the Tetranuclear Cu4S4 Cofactor of a Synthetic
4-Helix Bundle O. A. Kharenko, D. C. Kennedy, B. Demeler, M. J.
Maroney, and M. Y. Ogawa, J. Am.
Chem. Soc. 2005, 127,
7678.
|
|