Professor

Office: 210 Physical Sciences Laboratory Building
Phone: (419) 372-2044
Email: artbrec@bgsu.edu
Personal site: Visit

Biographical Facts
Joined the faculty in 1969
Ph.D., U.C.L.A. (1956)
B.S., City College of New York (1948)

Research Interests
Currently, we are studying the blood coagulation cascade and are examining the effect of acetaldehyde upon the coagulation components.  This relates directly to the effect of alcohol metabolites upon the enzymes, zymogens, protease inhibitors and glycosaminoglycans, such as heparin.  Additionally, we are chemically modifying heparin and studying the anticoagulant effects of its analogs.  Finally, the effect of acetaldehyde on hypertension, hypotension, pancreatitis, and emphysema are being explored.

In separate studies, we are quantitating the effect of protamine sulfate and other small peptides with hormonal potential on the interaction of blood coagulation factors with antithrombin III.