Table 10: Isostericity Matrix for cis Hoogsteen/Sugar Edge geometry. Both AA and UG have been observed crystallographically. (I) indicates pairs inferred from covariations observed in the 1089/1090 side-by-side pair in the 23S rRNA L11 binding site. (I*) indicate covariations only observed for mitochondrial sequences.
|
Sugar Edge |
|||||
|
Hoogsteen |
A |
C |
G |
U |
|
|
A |
I1 |
I1 |
I1 |
I1 |
|
|
C |
I1 |
I1 |
I1 |
I1 |
|
|
G |
(I1) |
X |
I1 |
X |
|
|
U |
I2 |
(I1) |
I1 |
I1 |
|