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- Ph. D., Utah State University
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- Office: 429C Life Sciences Building
- Phone: 1-419-372-0376
- Email: rwoodru@bgsu.edu
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- Research:
- Evolutionary genetics, Role of mutation in evolution and aging, Transposable
DNA elements, and Molecular
evolution. Drosophila
as model organism.
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- Curriculum Vitae (11/17/2009)
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Research Interests:
We
are involved in two main areas of genetic research with eukaryotic
organisms: The role of mutation in evolution and the genetics of
transposable DNA elements of Drosophila. In particular, we are
interested in the role of premeiotic clusters of mutation in evolution,
using experimental and theoretical techniques.
For abstracts of articles, go to: http://www.bgsu.edu/departments/biology/people/faculty/
Selected Publications:
Abstracts for the following articles can be found by going to PubMed on the NCBI
website. Type in Woodruff
R C to get all the abstracts.
Azad, P., Mingcai Zhang, and R. C. Woodruff. Rapid increase in viability due
to new beneficial mutations in Drosophila melanogaster. 2009.
Genetica, DOI 10.1007/s10709-009-9418-3.
Woodruff, R.C., and Mingcai Zhang. 2009. Adaptation from leaps in the dark. Journal
of Heredity 100: 7-10.
Ogura, K., R.C. Woodruff,
M. Itoh and I.A. Boussy.
2007. Long-term patterns of genomic P element content and P-M
characteristics of D. melanogaster in
eastern Australia. Genes & Genetic
Systems 82: 479-487.
Gong, Y., J.N. Thompson,
Jr., and R.C. Woodruff.
2006. Effect of deleterious
mutations on lifespan
in Drosophila melanogaster. Journal of Gerontology:
Biological Sciences 61A: 1246-1252.
Azad, P. and R.C. Woodruff.
2006. Mutation and
cloning efficiency.
Cloning
and Stem Cells 8: 237-239.
Woodruff, R.C., and
J.N. Thompson.
Jr. 2005. The fundamental theorem
of neutral evolution:
Rates of substitution
and mutation should factor in premeiotic clusters. Genetica 125:
333-339.
Gong, Y., J.N.
Thompson, Jr.,
and R.C. Woodruff. 2005. Deleterious
genomic mutation
rate for viability
in Drosophila melanogaster using concomitant
sibling controls.
Biology
Letters 1: 492-495.
Gong, Y., S.
Gu and R.C.
Woodruff. 2005. The influence
of premeiotic
clusters of mutation on indirect estimations of
mutation rate. Human
Heredity 60: 150-155.
Woodruff, R.C.,
J.N. Thompson,
Jr., and
S. Gu. 2004. Premeiotic clusters of mutation
and the cost
of natural
selection. Journal
of Heredity 95: 277-283.
Woodruff, R.C.,
J.P. Phillips
and A.J.
Hilliker. 2004. Increased spontaneous
DNA damage
in Cu/Zn
superoxide dismutase (SOD1) deficient Drosophila.
Genome
47:
1029-1035.

Teaching Articles:
Woodruff, R. C. and Katherine D. Onasch. The identification of hidden genetic
variation
(recessive visible mutations) in a natural population of Drosophila melanogaster.
2009.
In press. Drosophila Information Service. Vol
92.
Rex, Caitlin M., Sarah J. Rossiter, Amanda C. Lyons and R. C. Woodruff. Negative
synergistic epistasis in Drosophila melanogaster. 2009. In press. Drosophila
Information Service. Vol 92.
Benson, J.L., A.M. Boulton, C.W. Coates, A.C. Lyons, S.J. Rossiter and R. C.
Woodruff. Rare male mating advantage in Drosophila melanogaster. 2009. In press. Drosophila
Information Service. Vol 92.
Onasch, Katherine D. and R. C. Woodruff. 2008. Experimental observation of inbreeding
depression and heterosis in Drosophila melanogaster. Drosophila Information Service. 91: 151-155.
Onasch, Katherine D, Natalie Wiseman, Bethany Robinson, Mingcai Zhang, and R.
C. Woodruff. 2008. Experimental observation of overdominance (heterozygous
advantage) in Drosophila melanogaster. Drosophila Information Service. 91: 169-178.
Robinson, Bethany, Natalie Wiseman, Mingcai Zhang, Cynthia J. Staber and R. C.Woodruff.
2008. Identification of selfish genetic elements in natural populations
of Drosophila melanogaster. II. Segregation Distorter (SD). Drosophila Information Service. 91: 179-182.
Thompson, James N., Jr. Clayton N. Hallman, Christopher C. Challis, Jane T. Ma,
Kyley K. Makanani, Anna L. McGahan, Whitney D. Nall, Patience
O. Ozor, Sean P. Rogers, Katherine L. Shoush, Jessica L. Turner,
Hunter J. Wernick, Dusty M. Wiles, Rachel S. Yi, Tyler W. Kallsen,
Michael J. Hessler, Barbara Sfiejko-Mroczka, and R. C. Woodruff.
2008. A classroom test of predictions about Segregation Distorter
(SD) activity in Drosophila. Drosophila Information Service. 91: 183-185.
Onasch, Katherine D. and R. C. Woodruff. 2007. Changes in linkage disequilibrium
over time in Drosophila melanogaster for two sex-linked loci. Drosophila Information Service. 90: 177-186.
Robinson, Bethany, Natalie Wiseman and R. C. Woodruff. 2007. Identification of
selfish genetic elements in natural populations of Drosophila
melanogaster. I.P DNA elements. Drosophila Information Service. 90: 172-176.
Toth, Cynthia L, Jessica L. Heintzelman and R. C. Woodruff. 2007. Ultraviolet
(UV) light induced mutations in Drosophila melanogaster. Drosophila Information Service. 90: 169-171.
Thompson, J. N., jr. Clayton N. Hallerman, Jenna J. Hellack and R. C. Woodruff.
2006. Measuring natural selection using alcohol dehydrogenase
alleles. Drosophila Information Service. 89: 148-149.
Zhang, Mingcai and R. C. Woodruff. 2006. Confirmation of the Bateman’s principle:
a sexual selection exercise. Drosophila Information Service. 89: 143-148.
Woodruff, R. C. and J. N. Thompson, jr. 2005. Response to selection in the presence
and absence of genetic variation in Drosophila melanogaster. Drosophila Information Service. 88: 139-143.
Morgan, E., R. C. Woodruff and J. N. Thompson, jr. 2004. The interchromsomal
effect on recombination in Drosophila melanogaster. Drosophila Information Service, 87: 115-117.
Azad, P., R. C. Woodruff and J. N. Thompson, jr. 2004. Deleterious mutations
in natural populations of Drosophila melanogaster. Drosophila Information Service, 86: 165-168.
Woodruff, R. C. and James N. Thompson, jr. 2002. Use of the Drosophila melanogaster
zeste screen to identify aneuploidy induced by cold treatment. Drosophila Information Service, 85: 149-151.
Gu, Sheng, Yi Gong, Matthew Smith and R. C. Woodruff. 2002. The dominance value
of the Sb allele in Drosophila melanogaster. Drosophila Information Service, 85: 143-149.
Woodruff, R. C. and J. N. Thompson, jr. 2001. A one-generation, white-peach assay
for mariner DNA element activity in Drosophila simulans. Drosophila Information Service, 84: 213-215.
Thompson, J. N., jr., R. C. Woodruff, S. B. Gray, G. S. Hendrix and J. J. Hellack.
2000. Cellulose acetate measurement of Adh allele frequencies
is a simple exercise in population genetics. Drosophila Information Service 83: 203-205.
Woodruff, R. C. and J. N. Thompson, jr. 1999. A one-generation assay of induced
genetic damage. Drosophila Information Service, 82: 140-141.
Woodruff, R. C. and J. N. Thompson, jr. 1997. A teaching exercise combining Mendelian genetics and gene therapy concepts in Drosophila. Drosophila Information Service 80: 107-108.
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